Research reference
BPC-157
BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid peptide supplied as a lyophilised powder for laboratory research applications only.
Molecular information
Type
Pentadecapeptide
Length
15 amino acids
Formula
C62H98N16O22
Weight
1419.5 g/mol
CAS
137525-51-0
Form
Lyophilised powder
Vial sizes
5 mg / 10 mg
Classification
Regenerative peptide
Sequence
- 01Gly
- 02Glu
- 03Pro
- 04Pro
- 05Pro
- 06Gly
- 07Lys
- 08Pro
- 09Ala
- 10Asp
- 11Asp
- 12Ala
- 13Gly
- 14Leu
- 15Val
GEPPPGKPADDAGLV
Research overview
BPC-157 is derived from a partial sequence of a protein identified in human gastric juice. It is studied in laboratory models for its role in angiogenesis (blood vessel formation), collagen formation during tissue remodelling, and nitric oxide signalling pathways relevant to vascular research.
Common research focus areas
Laboratory research use only
This product is supplied strictly for laboratory research use. It is not a medicine, food, cosmetic, or dietary supplement, and is not for human or animal consumption. Any use outside a documented laboratory research protocol is prohibited.
Handling
For laboratory use, reconstitute with a sterile diluent appropriate to the research protocol, introducing the diluent slowly against the vial wall to minimise peptide degradation. Do not shake.
Published research
- Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healingGwyer D et al. · Cell and Tissue Research · 2019 · ReviewPMID 30915550
- Emerging use of BPC-157 in orthopaedic sports medicine: a systematic reviewVasireddi N et al. · HSS Journal · 2025 · Systematic reviewPMID 40756949
- Regeneration or risk? A narrative review of BPC-157 for musculoskeletal healingMcGuire FP et al. · Current Reviews in Musculoskeletal Medicine · 2025 · ReviewPMID 40789979
- Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulationHsieh MJ et al. · Journal of Molecular Medicine · 2017 · PreclinicalPMID 27847966
- Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growthStaresinic M et al. · Journal of Orthopaedic Research · 2003 · PreclinicalPMID 14554208
- Enhancement by PL 14736 of granulation and collagen organization in healing wounds and the potential role of egr-1 expressionTkalcević VI et al. · European Journal of Pharmacology · 2007 · PreclinicalPMID 17628536
- Stable gastric pentadecapeptide BPC 157 as a therapy and safety key: modulating angiogenesis and the NO-systemSikiric P et al. · Pharmaceuticals · 2025 · ReviewPMID 40573323
Evidence status
Most published research on BPC-157 has been carried out in rodent models by a small number of research groups. Human data is limited to small, uncontrolled studies. BPC-157 is not approved by any medicines regulator and is included on the World Anti-Doping Agency Prohibited List.







