GHK-CU

£19.99

Research-grade GHK-Cu, supplied as lyophilised powder in 20 mg and 50 mg vials. For laboratory research use only. Not for human or animal consumption.

Shipped by Royal Mail, packed with ice packs to keep your order cool in transit. UK delivery £3.99.

SKU: CU-GHKCU
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Research reference

GHK-CU

Cell and animal evidence, limited clinical data

GHK-Cu is the copper(II) complex of GHK (glycyl-L-histidyl-L-lysine), a naturally occurring tripeptide first identified in human plasma. It is supplied as a lyophilised powder for laboratory research applications only.

Molecular information

Type

Copper peptide complex

Length

3 amino acids

Formula

C14H22CuN6O4

Weight

401.9 g/mol

CAS

89030-95-5

Form

Lyophilised powder

Vial sizes

20 mg / 50 mg

Classification

Copper peptide

Sequence

  • 01Gly
  • 02His
  • 03Lys

GHK + Cu(II)

Research overview

GHK was first described in 1973 as a factor in human plasma, and it binds copper(II) with high affinity. Laboratory research examines the influence of GHK-Cu on fibroblast activity, collagen, elastin and glycosaminoglycan synthesis, and wound-healing signalling relevant to dermatological research models.

Common research focus areas

  • Collagen synthesis studies
  • Fibroblast signalling research
  • Wound-healing models
  • Skin remodelling research

Laboratory research use only

This product is supplied strictly for laboratory research use. It is not a medicine, food, cosmetic, or dietary supplement, and is not for human or animal consumption. Any use outside a documented laboratory research protocol is prohibited.

Handling

For laboratory use, reconstitute with a sterile diluent appropriate to the research protocol, introducing the diluent slowly against the vial wall to minimise peptide degradation. Do not shake.

Published research

  • Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liverPickart L, Thaler MM · Nature New Biology · 1973 · DiscoveryPMID 4349963
  • Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+Maquart FX et al. · FEBS Letters · 1988 · In vitroPMID 3169264
  • The human tri-peptide GHK and tissue remodelingPickart L · Journal of Biomaterials Science, Polymer Edition · 2008 · ReviewPMID 18644225
  • GHK peptide as a natural modulator of multiple cellular pathways in skin regenerationPickart L et al. · BioMed Research International · 2015 · ReviewPMID 26236730
  • Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene dataPickart L, Margolina A · International Journal of Molecular Sciences · 2018 · ReviewPMID 29986520
  • Topically applied GHK as an anti-wrinkle peptide: advantages, problems and prospectiveMortazavi SM et al. · BioImpacts · 2025 · ReviewPMID 39963574

Evidence status

Most published research on GHK-Cu comes from cell culture and animal studies, and a large share of it from a small number of research groups. GHK-Cu is widely used as a cosmetic ingredient (INCI name copper tripeptide-1), but controlled clinical studies are scarce. It is not approved as a medicine by any regulator.

Additional information

Vial Size

20 mg, 50 mg

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